Apple Cider Vinegar is a vinegar type made by fermenting apple cider. In this process the sugar present in the apple cider gets broken by the yeast and bacteria into alcohol and vinegar. Apple cider vinegar consists of acetic acid as well as citric, lactic and malic acids. Apple cider vinegar is yellow brown in color and is sold unfiltered. This unfiltered apple cider vinegar is available in the health food stores and also in grocery stores. The other vinegar types are white vinegar, red wine vinegar, balsamic vinegar and rice wine vinegar. They are used in cooking as well as are good for health purposes. Apple cider vinegar was believed to have been used by Hippocrates as health tonic and the American soldiers also made use of the same to combat indigestion ad pneumonia. The intriguing aspect of this vinegar is that it has abundant health benefits. It can decrease the blood glucose levels. It is effective for people suffering from diabetes and weight loss.

Bioperine- Basically a pure and safe nutritional supplement of piperine, Bioperine can have several positive effects on our body. It contains about ninety five percent of piperine that is known to enhance the bioavailability of nutrients. As a result, bioperine intake helps in rapid absorption of nutrients from the gastrointestinal tract. Owing to its affinity for the fatty tissue, it even interacts with the lipid component of the intestinal cell membrane thereby allowing further nutrient permeability. It is quite popular due to its ability to enhance thermogenesis. This is how it works - the piperine present in bioperine stimulates the release of catecbolamines that trigger thermogenesis in the GI tract thus, making more energy available for digestion. It can be combined with other nutrients like the way it is used in Thermadrol to allow more of the ingredients to be absorbed by the body.

Caffeine is the most widely used legal stimulant of the central nervous system and is also used in Thermadrol, with characteristics that have been described as restoration of alertness and removing from drowsiness. Coffee, Tea, many soft drinks and energy drinks as well as nutrition supplements have this ingredient, which is a psychoactive substance, a xanthine alkaloid that can act as a adenosine receptor antagonist, as well as a phosphodiesterase inhibitor. Although regular use of caffeine seems to have nootropic effects, enhancing cognitive abilities, it also is known to provide long term effects on the nervous and cardiovascular system, like in one study it was proven that people with normal to low blood pressure have the possibility of developing a heart disease significantly reduced, Thermadrol uses a low dose of caffeine, the way it should be done so you do not get the energy crash like other weight loss supplements.

Cayenne, which contains Capsaicin, a thermogenic substance. A thermogenic raises your core temperature, which allows you to burn more calories from food, particularly when eating a high fat meal.

Chromium Picolinate is, besides chromium polynicotinate, a nutritional supplement designed to avoid or treat chromium deficiency. Insulin requires some modest levels of chromium in order to utilize glucose in healthy individuals. There is no record of chromium deficiency occurrences in regular population, only prolonged dieters in clinically observed and controlled obesity reduction treatments have registered any. Clinical trials have suggested that chromium picolinate may have antidepressant qualities, when applied to patients with atypical depression. Further observation signaled a reduction in carbohydrate cravings and seemed to regulate appetite. These results led to the incorporation of chromium picolinate into supplements for athletes who are working on body development and are looking to lose weight. It has been also observed that chromium picolinate is able to boost the blood levels of insulin for a limited time.

Citrus Aurantium is the Latin name for a citrus tree which grows bitter oranges. Traditionally being used by Chinese medicine and herbologists, the extract of the orange and the peel was used as a dietary supplement in concoctions with other herbs to suppress appetite. While other active ingredients of the citrus aurantium may contribute and even promote the effect, the main ingredient used in all weight loss products is synephrine, an alkaloid similar to ephedrine. It is a phenethylamine; it influences the alpha1 adrenergic receptor, constricting blood vessels, additionally increasing the heart rate and the blood pressure. In most cases the use of synephrine is paired with a diet and body building plan, where weight loss and muscle building is essential.

Fennel Seed or Sauf is derived from the herb Foeniculum vulgare. It is commonly used for digestive problems such as relieving gas, cramps and indigestion. It is very rich in minerals particularly magnesium. It also has anethol that inhibits muscle spasms particularly in the intestinal tract. Fennel Seed also helps in increasing the production of bile. It may also be used for de-worming and ridding the intestine of other such parasites. Fennel Seed also possess anti-microbial properties and may act as a decongestant. It may also be used as diuretic. It is also effective in aiding weight loss because it suppresses appetite and food cravings. It also reduces water retention in the body.

Ginger Root has been used as herbal medicine in India, Asia, and Arab countries for a long time. People in China have been using this knotted, thick, underground stem or rhizome of the plant Zingiber officinale to improve digestion for over two thousand years. Ginger was also found effective in the treatment of health conditions such as heart problems, arthritis, colic, and diarrhea. Ginger is also a popular cooking spice in different cuisines. The magic herb can also help a great deal in pregnancy, motion sickness, and cancer chemotherapy since it aids in preventing or treating nausea and vomiting associated with it. Many women consume ginger to reduce the pain during menstrual periods. Ginger is also used to reduce inflammation and combat inflammation-related problems such as arthritis and ulcerative colitis. You may buy fresh ginger root or go for other variations like ginger extracts, capsules, and oils.

Green Tea Extract is currently being promoted by the health conscious community as a weight loss product, which does not do this incredible concoction of helpful ingredients justice. Many green tea extracts nowadays exclude caffeine, to avoid the associated side effects and lower the ingestion of this legal addictive stimulant. The main characteristic of the green tea extract should be the antioxidative effect, which surpasses Vitamin C twentyfold. But the other traits are not to be forgotten, it is anti-inflammatory, anti-carcinogen and anti-radiation. The unique combination of green tea catechins, derivatives of apicatechin, and flavonoids, which belong to the same family, are proven scavengers of free radicals and an unavoidable addition to any dietary supplement combination, body building or weight loss as the target objective.

Gymnema Sylvestre is an herb stemming from southern and central India where it has been used for nearly 2000 years as a naturopathic treatment for diabetes.

Hydrocitric Acid (HCA), also called hydroxycitric acid, is an acidic chemical compound that is produced in fruit of Garcinia cambogia plant. Hydrocitric acid helps reduce appetite, thus aiding in weight loss. It speeds up metabolism that in turn burns fat and carbohydrates, oxygenating, and converting them into energy. It stimulates the liver. Fat burning occurs within cell mitochondrion, this property one of the key benefits of taking HCA of the Garcinia. Hydrocitric acid does not decrease the muscular bulk; it enhances fat burning and at the same time burning or oxidation of proteins is stopped, which means that corporal fat is reduced but not the muscle tissue. It also is beneficial for people having hypoglycemia as it decreases the effect of lack of sugar or food.

L-Carnitine , a naturally occurring non-essential amino acid which boosts its own production when combined with Vitamin C. L-carnitine transports fatty acids like triglycerides into the mitochondria and converts it into energy. Its antioxidant properties are believed to affect the heart muscles positively. L-cartinine deficiency is a rare case. However, fatigue, muscle-cramps and pre-mature aging are some of its deficiency signs. L-carnitine is highly found in dairy products and red meat. In foods like legumes, nuts, grains, fresh fruits, vegetables and cereals although the level of L-caritine is not high, it promotes production. L-carnitine is not known to cause any toxic effect, but an overdose of carnitine i.e. 1000mg daily can cause diarrhea, stomach cramps, nausea and vomiting. Research prove that adding L-carnitine to our daily diet increases metabolism promotes weight loss and maintains a healthy level of blood glucose.

L-Tyrosine is a non-essential amino acid, which is used by the cells in order to synthesize the proteins and appears to help stabilize ones mood during periods of high stress levels.

Licorice Root is cultivated in southern as well as central Europe. Licorice root is extensively used as flavor in candies and as well as in syrups, cough drops, laxatives and tonics. The licorice root is also useful in flavoring various types of beer, gelatins, meat products, puddings and frozen dairy desserts. Licorice is commonly found in all the Chinese herb combinations so that it maintains other herbs as well as promotes vitality. Licorice is a source of silicon, magnesium and thiamine. It is available in liquid extract and is helpful for people having problems with swallowing capsule. Licorice root capsule can be taken three times a day. Licorice root is useful for various ailments such as baldness, asthma, canker sores, athlete’s foot, depression, chronic fatigue, flu, colds, dandruff, coughs, gingivitis, emphysema, heartburn, viral infections, HIV, ulcers, fungal infections, tooth decay and liver problems. This root has anti-depressant compounds and is one of the impressive herbal medicines.

Pantothenic Acid is thought to reduce lactic acid accumulation in athletes, may improve oxygen utilization efficiency, and is believed to improve the body's ability to heal and possibly help in reducing acne

Phenylalanine is an essential amino acid that plays an important role in the formation of proteins. It is converted into tyrosine in the body which stimulates the production of dopamine, epinephrine and norepinephrine. It helps treat and manage the symptoms of Attention Deficit Hyperactivity Disorder (ADHD), depression, and Parkinson’s disease. It also alleviates the symptoms from alcohol withdrawal. It also has the ability to reduce pains caused by osteoarthritis, rheumatoid arthritis and premenstrual syndrome (PMS). Phenylalanine also treats vitiligo, a skin pigmentation disorder. Phenylalanine may also help in weight loss because it aids in suppressing the appetite and cravings, and at the same time, it promotes the production of energy.

Vitamin B12, also known as cobalamin, which is naturally found in foods such as fish, milk and milk products, eggs, meat and poultry. Vitamin B12 is important for good health, necessary for the proper digestion and absorption of foods and for normal metabolism of carbohydrates, and fat. It helps maintain healthy nerve cells and red blood cells and is needed to make DNA. Vitamin B12 is bound to the protein in food. Hydrochloric acid in the stomach releases B12 from protein during digestion. Unlike other water-soluble nutrients, vitamin B12 is stored in the liver, kidney, and other body tissues. It can take several years before signs of the deficiency appear due to poor dietary intake. Vitamin B12 functions as a "methyl donor." A methyl donor is a compound that carries and donates methyl groups to other molecules, including cell membrane components and neurotransmitters. As a methyl donor vitamin B12 is involved in homocysteine metabolism and plays a critical role in proper energy metabolism, immune function, and nerve function. Therefore, vitamin B12 is clearly an added benefit for anyone wanting to lose weight, as without it, metabolism is not at its peak potential.

Vitamin B6, which active form pyridoxal phosphate or otherwise known as PLP and pyridoxal-5’-phosphate, is a prosthetic group of tightly bound cofactors responsible for many reactions within the amino acid metabolism and the manipulation of the enzymatic reaction behind the release of glucose from glycogen. Vitamin B6 generally comprises three organic compounds, pyridoxine, pyridoxal and pyridoxamine, all of them heterocyclic organic compounds that are converted in the human body to the active pyridoxal phosphate form. There are three reactions attributed to PLP, namely transamination, alpha elimination and beta elimination. Over one hundred and forty enzyme activities depend on pyridoxal phosphate, neurotransmitter and histamine synthesis, synthesis and function of hemoglobin, and gene expression. As a cofactor, PLP is active in amino acid metabolism, glucogenesis and lipid metabolism.

White Willow Bark is used as an anti-inflammatory and treats pains such as joint pain, flu, fever, back pain and osteoarthritis.

Yerba Matte or Ilex paraguariensis commonly grows in South America. It contains about twenty four vitamins and minerals, fifteen amino acids, eleven types of polyphenols, caffeine, and contains a high level of antioxidants. It is considered to be the most balanced stimulant and revered as the “drink of the gods”. It contains xanthine alkaloids such as theobromine, caffeine and theophylline, and saponins that stimulate the immune system, enhance the memory and focus, and suppress appetite. Yerba Mate also helps regulate the blood sugar and cholesterol level. It also helps burn the fat and fight free radical damages to cells that may cause cancer and aging. It also helps in cleansing the blood, and may act as a diuretic.

The Thermadrol formula is just so powerful, not only does it contain all of these ingredients, the dosages are maxed out, I just don't understand how it is sold for around the same prices as a basic watered down big box retailer weight loss product.